Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096358 | 0.90 | F10 (0.46) | MAPK1F10SCN2ASCN10AKDM4E | |
| SCHEMBL1095301 | 0.79 | POLB (0.46) | MAPK1F10KDM4ELMNAHPGD | |
| SCHEMBL1097790 | 0.78 | MAPK1 (0.43) | MAPK1F10HPGDTSHR | |
| SCHEMBL1096929 | 0.78 | F10 (0.44) | F10SCN2ASCN10AKDM4ELMNA | |
| SCHEMBL1097008 | 0.78 | F10 (0.44) | F10SCN2ASCN10AKDM4ELMNA | |
| SCHEMBL1096071 | 0.77 | F10 (0.43) | F10SCN2ASCN10AKDM4ELMNA | |
| SCHEMBL1158898 | 0.77 | KDM1A (0.53) | F10SCN2ASCN10AKDM4ELMNA | |
| SCHEMBL1106607 | 0.77 | F10 (0.46) | MAPK1F10SCN2ASCN10AKDM4E | |
| SCHEMBL1097001 | 0.76 | F10 (0.58) | MAPK1F10KDM4ELMNAHPGD | |
| SCHEMBL1096809 | 0.75 | LMNA (0.42) | MAPK1F10SCN2ASCN10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |