Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 13/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FABP6 | P51161 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280859 | 0.85 | KAT2B (0.38) | KAT2BBPTFSMN1; SMN2 | |
| SCHEMBL2743217 | 0.81 | EPHX2 (0.43) | KAT2BBPTFEPHX2ALDH1A1 | |
| SCHEMBL24314234 | 0.81 | EPHX2 (0.43) | KAT2BBPTFEPHX2ALDH1A1 | |
| SCHEMBL8280863 | 0.81 | EPHX2 (0.43) | KAT2BBPTFEPHX2ALDH1A1 | |
| SCHEMBL12227439 | 0.80 | EPHX2 (0.34) | EPHX2ALDH1A1FABP6 | |
| SCHEMBL12852528 | 0.78 | PSEN1 (0.39) | KAT2BBPTF | |
| SCHEMBL18912347 | 0.76 | CA1 (0.53) | KAT2BBPTF | |
| SCHEMBL26727078 | 0.75 | KAT2B (0.38) | KAT2BBPTFALDH1A1 | |
| SCHEMBL8280860 | 0.74 | NAMPT (0.38) | KAT2B | |
| SCHEMBL16078083 | 0.70 | PSEN1 (0.38) | KAT2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080389-A1 | INDAZOLE-CARBOXAMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | THERAVANCE, INC. (US) | 2005-09-01 | — | — | WO | disclosed |