Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281052 | 0.92 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CA2POLBLMNA | |
| SCHEMBL8543593 | 0.89 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CA2POLBLMNA | |
| SCHEMBL23633829 | 0.83 | CYP3A4 (0.47) | ALDH1A1CYP3A4CA2POLBLMNA | |
| SCHEMBL26429167 | 0.79 | POLB (0.51) | ALDH1A1CYP3A4CA2POLBLMNA | |
| SCHEMBL8281048 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CA2POLBLMNA | |
| SCHEMBL24973032 | 0.78 | NR1H3 (0.39) | ALDH1A1TSHRMAPK1MAOBKMT2A | |
| SCHEMBL8281045 | 0.75 | TSHR (0.45) | ALDH1A1POLBTSHRMAPK1NPC1 | |
| SCHEMBL28221097 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2POLBLMNA | |
| SCHEMBL8281041 | 0.72 | TSHR (0.43) | ALDH1A1CYP3A4POLBLMNATSHR | |
| SCHEMBL14629715 | 0.71 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CA2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8779055-B2 | Hydrophobically modified alkylene oxide urethane polymer | ROHM AND HAAS COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-8779055-B2 | Hydrophobically modified alkylene oxide urethane polymer | ROHM AND HAAS COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| EP-2594595-A1 | Hydrophobically modified alkylene oxide urethane polymer | Rohm and Haas Company (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20120130000-A1 | HYDROPHOBICALLY MODIFIED ALKYLENE OXIDE URETHANE POLYMER | ROHM AND HAAS COMPANY | 2012-05-24 | — | — | US | disclosed |
| US-20120130000-A1 | HYDROPHOBICALLY MODIFIED ALKYLENE OXIDE URETHANE POLYMER | ROHM AND HAAS COMPANY | 2012-05-24 | — | — | US | disclosed |
| EP-2455412-A1 | Hydrophobically modified alkylene oxide urethane polymer | Rohm and Haas Company (US) | 2012-05-23 | — | — | EP | disclosed |