Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 17/20 | 0.52 |
| ▸ | ATF1 | P18846 | 13/20 | 0.52 |
| ▸ | XPO1 | O14980 | 5/20 | 0.51 |
| ▸ | JUN | P05412 | 5/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.50 |
| ▸ | RELA | Q04206 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79014 | 0.82 | NFKB1 (0.60) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL480176 | 0.79 | XPO1 (0.62) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL9564861 | 0.77 | NFKB1 (0.58) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL8518174 | 0.77 | NFKB1 (0.62) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL17315283 | 0.77 | NFKB1 (0.58) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL9564875 | 0.76 | NFKB1 (0.57) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL15290081 | 0.73 | NFKB1 (0.56) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL473934 | 0.73 | ATF1 (0.62) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL27853425 | 0.73 | NFKB1 (0.43) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL20839631 | 0.72 | NFKB1 (0.46) | NFKB1ATF1XPO1JUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005074939-A1 | COMBINATION OF CB2 MODULATORS AND PDE4 INHIBITORS FOR USE IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2005-08-18 | — | — | WO | disclosed |