Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | C1R | P00736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827978 | 0.93 | FFAR1 (0.42) | FFAR1ARKMT2APDE10APIK3C3 | |
| SCHEMBL826935 | 0.89 | FFAR1 (0.44) | FFAR1ARKMT2APDE10APIK3C3 | |
| SCHEMBL827287 | 0.89 | FFAR1 (0.43) | FFAR1ARKMT2APDE10APIK3C3 | |
| SCHEMBL828191 | 0.87 | FFAR1 (0.41) | FFAR1PDE10APIK3C3KIT | |
| SCHEMBL826952 | 0.85 | FFAR1 (0.46) | FFAR1ARKMT2APDE10APIK3C3 | |
| SCHEMBL828049 | 0.85 | FFAR1 (0.42) | FFAR1ARPDE10APIK3C3KIT | |
| SCHEMBL828012 | 0.84 | FFAR1 (0.38) | FFAR1ARPDE10APIK3C3KIT | |
| SCHEMBL828026 | 0.83 | FFAR1 (0.43) | FFAR1ARKMT2APDE10APIK3C3 | |
| SCHEMBL828548 | 0.83 | FFAR1 (0.42) | FFAR1ARKMT2APDE10APIK3C3 | |
| SCHEMBL828592 | 0.83 | FFAR1 (0.41) | FFAR1ARPDE10APIK3C3C1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143274-B2 | 1-(2H)-isoquinolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-03-27 | — | — | US | disclosed |