Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830075 | 0.95 | EHMT2 (0.52) | MMP1MMP3MMP9SIRT2SIRT1 | |
| SCHEMBL10064039 | 0.86 | EHMT2 (0.44) | MMP1MMP3MMP9EHMT2 | |
| SCHEMBL830079 | 0.84 | HDAC3 (0.47) | MMP1MMP3MMP9EHMT2HDAC8 | |
| SCHEMBL829775 | 0.83 | EHMT2 (0.54) | EHMT2HDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL830026 | 0.83 | EHMT2 (0.46) | MMP1MMP3MMP9EHMT2 | |
| SCHEMBL29193437 | 0.82 | MMP1 (0.59) | MMP1MMP3MMP9SIRT2SIRT1 | |
| SCHEMBL10064199 | 0.82 | EHMT2 (0.47) | MMP1MMP3MMP9SIRT2SIRT1 | |
| SCHEMBL830001 | 0.81 | EHMT2 (0.50) | MMP1MMP3MMP9SIRT2SIRT1 | |
| SCHEMBL11252054 | 0.81 | MMP1 (0.57) | MMP1MMP3MMP9SIRT2SIRT1 | |
| SCHEMBL23454666 | 0.78 | MEN1 (0.58) | MMP1MMP3MMP9SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178783-A1 | HDAC INHIBITORS | LIXTE BIOTECHNOLOGY, INC. | 2012-07-12 | — | — | US | disclosed |
| US-8143445-B2 | HDAC inhibitors | LIXTE BIOTECHNOLOGY, INC. (US) | 2012-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178783-A1 | HDAC INHIBITORS | HDAC3, HDAC4, HDAC7 | MMP1 1804/4885MMP3 472/4885MMP9 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.