Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670592 | 0.88 | HRH3 (0.57) | HRH3KCNH2 | |
| SCHEMBL18553710 | 0.80 | HRH1 (0.53) | HRH3SLC18A3HPGD | |
| SCHEMBL3038636 | 0.79 | HRH1 (0.55) | HRH3SLC18A3HPGD | |
| SCHEMBL15000364 | 0.76 | HRH1 (0.55) | HRH3SLC18A3 | |
| SCHEMBL18553711 | 0.75 | HRH1 (0.63) | HRH3SLC18A3 | |
| SCHEMBL8285812 | 0.74 | ACACB (0.50) | SLC18A3 | |
| SCHEMBL12911279 | 0.74 | MCHR1 (0.50) | HRH3KCNH2SMN1; SMN2 | |
| SCHEMBL2366436 | 0.72 | HRH1 (0.63) | HRH3SLC18A3 | |
| SCHEMBL4620042 | 0.72 | HRH3 (0.61) | HRH3 | |
| SCHEMBL25176717 | 0.71 | CHRNB2 (0.51) | SLC18A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |