Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284448 | 0.91 | TRPC5 (0.48) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL8284400 | 0.86 | TRPC5 (0.42) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL8284447 | 0.84 | TRPC5 (0.56) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL8283653 | 0.81 | TRPC5 (0.50) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL8285540 | 0.81 | TRPC5 (0.46) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL4857710 | 0.80 | TRPC5 (0.39) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL8248590 | 0.80 | TRPC5 (0.47) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL8283650 | 0.79 | TRPC5 (0.47) | TRPC5MAPK1NPSR1TDP1ALDH1A1 | |
| SCHEMBL4864386 | 0.79 | TRPC5 (0.38) | TRPC5MAPK1ALDH1A1USP2MAPT | |
| SCHEMBL8241916 | 0.78 | TRPC5 (0.49) | TRPC5MAPK1NPSR1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058871-A1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |