SCHEMBL828461

SCHEMBL828461

CCCC(C#N)N=NC(C#N)CCC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188122 1.00 TSHR (0.33) TSHR
SCHEMBL11065908 0.84 TSHR (0.42) TSHR
SCHEMBL9619297 0.84 TSHR (0.42) TSHR
SCHEMBL5955549 0.82 TSHR (0.40) TSHR
SCHEMBL5955545 0.82 TSHR (0.40) TSHR
SCHEMBL5404418 0.80 TSHR (0.39) TSHR
SCHEMBL28340905 0.80
SCHEMBL28100079 0.79
SCHEMBL16220 0.77 TSHR (0.32) TSHR
SCHEMBL6673858 0.77 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175640-B Photochromic soft contact lens compositions and methods for making same 梅迪奥斯株式会社 2021-03-23 CN claimed
EP-3424688-B1 METHOD FOR MANUFACTURING BLUE LIGHT-BLOCKING SOFT CONTACT LENS, AND SOFT CONTACT LENS MANUFACTURED BY USING SAME MEDIOS CO LTD (KR) 2020-11-18 EP claimed
EP-3363862-B1 PHOTOCHROMIC SOFT CONTACT LENS COMPOSITION AND METHOD FOR PREPARING SAME MEDIOS CO LTD (KR) 2020-11-11 EP claimed
EP-3424688-A1 METHOD FOR MANUFACTURING BLUE LIGHT-BLOCKING SOFT CONTACT LENS, AND SOFT CONTACT LENS MANUFACTURED BY USING SAME Medios Co Ltd (KR) 2019-01-09 EP claimed
EP-3363862-A1 PHOTOCHROMIC SOFT CONTACT LENS COMPOSITION AND METHOD FOR PREPARING SAME Medios Co Ltd (KR) 2018-08-22 EP claimed
EP-1381633-B9 SYNTHESIS OF VINYL POLYMERS BY CONTROLLED RADICAL POLYMERIZATION PPG IND OHIO INC (US) 2010-03-31 EP claimed
US-7619040-B2 Compositions containing copolymers of olefinic monomers PPG INDUSTRIES OHIO, INC. (US) 2009-11-17 US claimed
EP-1381633-B1 SYNTHESIS OF VINYL POLYMERS BY CONTROLLED RADICAL POLYMERIZATION PPG IND OHIO INC (US) 2009-02-25 EP claimed
EP-1732955-B1 METHOD OF MAKING COPOLYMERS CONTAINING OLEFINIC TYPE MONOMERS PPG IND OHIO INC (US) 2008-10-22 EP claimed
US-7351781-B2 Synthesis of vinyl polymers by controlled radical polymerization PPG INDUSTRIES OHIO, INC. (US) 2008-04-01 US claimed
US-7323529-B2 Method of making copolymers containing olefinic type monomers PP6 INDUSTRIES OHIO, INC. (US) 2008-01-29 US claimed
JP-2007512418-A 2007-05-17 JP claimed
EP-1732955-A2 METHOD OF MAKING COPOLYMERS CONTAINING OLEFINIC TYPE MONOMERS PPG Industries Ohio, Inc. (US) 2006-12-20 EP claimed
WO-2005054305-A2 METHOD OF MAKING COPOLYMERS CONTAINING OLEFINIC TYPE MONOMERS PPG INDUSTRIES OHIO, INC. (US) 2005-06-16 WO claimed
US-20050131178-A1 Synthesis of vinyl polymers by controlled radical polymerization WHITE DANIELA (US) 2005-06-16 US claimed
US-20050113515-A1 Method of making copolymers containing olefinic type monomers PPG INDUSTRIES OHIO, INC. 2005-05-26 US claimed
US-20040143079-A1 Compositions containing copolymers of isobutylene type monomers PPG INSUSTRIES OHIO, INC. 2004-07-22 US claimed
US-6677422-B2 MIXING MOLAR EXCESS OF DONOR MONOMER WITH ETHYLENICALLY UNSATURATED ACCEPTOR MONOMER, POLYMERIZING IN PRESENCE OF FREE RADICAL POLYMERIZATION INITIATOR, FORMING POLYMER CONTAINING ALTERNATING DONOR-ACCEPTOR SEGMENTS PPG INDUSTRIES OHIO, INC. 2004-01-13 US claimed
US-20030171515-A1 Method of making alternating copolymers of isobutylene type monomers PPG INDUSTRIES OHIO, INC. 2003-09-11 US claimed
US-20030018151-A1 Synthesis of vinyl polymers by controlled radical polymerization PPG INDUSTRIES OHIO, INC. 2003-01-23 US claimed