SCHEMBL5404418

SCHEMBL5404418

CCCCCCCCC(C#N)/N=N\C(C#N)CCCCCCCC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.38
DNM1 Q05193 2/20 0.37
THRB P10828 1/20 0.36
OPRM1 P35372 1/20 0.36
GPR84 Q9NQS5 3/20 0.34
FDPS P14324 3/20 0.34
SPHK1 Q9NYA1 1/20 0.34
FFAR1 O14842 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5955549 0.98 TSHR (0.40) TSHRLMNADNM1THRBOPRM1
SCHEMBL5955545 0.98 TSHR (0.40) TSHRLMNADNM1THRBOPRM1
SCHEMBL11065908 0.91 TSHR (0.42) TSHRDNM1FDPS
SCHEMBL9619297 0.91 TSHR (0.42) TSHRDNM1FDPS
SCHEMBL9241708 0.83 OPRM1 (0.32) TSHROPRM1
SCHEMBL828461 0.80 TSHR (0.33) TSHR
SCHEMBL28457406 0.79 LMNA (0.40) TSHRLMNA
SCHEMBL9769445 0.77 MIF (0.32)
SCHEMBL24044418 0.75 TSHR (0.46) TSHRLMNADNM1THRBOPRM1
SCHEMBL13601912 0.75 TSHR (0.46) TSHRLMNADNM1THRBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285373-B2 Polymer and chemically amplified resist composition containing the same KOREA KUMHO PETROCHEMICAL CO., LTD (KR) 2007-10-23 US disclosed
US-20050153236-A1 Novel polymer and chemically amplified resist composition containing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2005-07-14 US disclosed