Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | CD44 | P16070 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3635791 | 0.98 | NOS2 (0.48) | NOS2CD44CYP3A4TDP1TSHR | |
| SCHEMBL4252594 | 0.89 | SKP2 (0.48) | NOS2CD44CYP3A4TDP1TSHR | |
| Hydrogen Sulfide SCHEMBL27537530 | 0.88 | SKP2 (0.47) | NOS2CD44CYP3A4TDP1TSHR | |
| SCHEMBL28849209 | 0.88 | CD44 (0.45) | NOS2CD44CYP3A4TDP1TSHR | |
| SCHEMBL3697918 | 0.86 | CYP3A4 (0.43) | NOS2CD44CYP3A4TDP1TSHR | |
| SCHEMBL6825844 | 0.86 | KCNH2 (0.46) | CD44CYP3A4TDP1TSHRSKP2 | |
| SCHEMBL21385098 | 0.86 | KCNH2 (0.46) | CD44CYP3A4TDP1TSHRSKP2 | |
| SCHEMBL28289695 | 0.86 | KCNH2 (0.46) | CD44CYP3A4TDP1TSHRSKP2 | |
| SCHEMBL15050026 | 0.84 | NOS2 (0.48) | NOS2CD44TSHRDHFRALDH1A1 | |
| SCHEMBL28287495 | 0.83 | CD44 (0.48) | NOS2CD44CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857657-A | Preparation of hexenedioic acid diesters | RHONE-POULENC CHIMIE (FR) | 1989-08-15 | — | — | US | claimed |
| CN-215179881-U | Ion mobility spectrometer for rapidly detecting methamphetamine in presence of nicotine | 中国科学院合肥物质科学研究院 | 2021-12-14 | — | — | CN | disclosed |
| CN-113109417-A | Ion mobility spectrometer for rapidly detecting methamphetamine in presence of nicotine | 中国科学院合肥物质科学研究院 | 2021-07-13 | — | — | CN | disclosed |
| CN-109864894-A | The composition of the excellent storage stability of high alkalinity filler is used | 株式会社松风 | 2019-06-11 | — | — | CN | disclosed |
| CN-104862756-B | The conducting polymer of Direct Electrochemistry synthesis doping on metal alloy | 波音公司 | 2019-05-03 | — | — | CN | disclosed |
| EP-1697345-B1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2008-03-12 | — | — | EP | disclosed |
| WO-2005058871-A1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
| EP-0272191-B1 | PROCESS FOR THE PREPARATION OF DIESTERS OF HEXENEDIOIC ACID | RHONE-POULENC CHIMIE (FR) | 1991-02-27 | — | — | EP | disclosed |
| US-4857657-A | Preparation of hexenedioic acid diesters | RHONE-POULENC CHIMIE (FR) | 1989-08-15 | — | — | US | disclosed |
| EP-0272191-A1 | Process for the preparation of diesters of hexenedioic acid | RHONE-POULENC CHIMIE (FR) | 1988-06-22 | — | — | EP | disclosed |