Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 12/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | PRMT9 | Q6P2P2 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867568 | 1.00 | AHCY (0.50) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4862505 | 1.00 | AHCY (0.50) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4862526 | 1.00 | AHCY (0.50) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4862517 | 1.00 | AHCY (0.50) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL14279838 | 1.00 | AHCY (0.50) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4862183 | 0.92 | AHCY (0.49) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4862230 | 0.92 | AHCY (0.49) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4863149 | 0.92 | AHCY (0.49) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL4862163 | 0.92 | AHCY (0.49) | AHCYPRMT5PRMT3PRMT9CARM1 | |
| SCHEMBL14279867 | 0.92 | AHCY (0.49) | AHCYPRMT5PRMT3PRMT9CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058228-A2 | COMT INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | disclosed |