Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004572 | 0.79 | REN (0.42) | RXFP1ALDH1A1TSHR | |
| SCHEMBL2813423 | 0.78 | CTSC (0.45) | NAMPTALDH1A1TSHR | |
| SCHEMBL3071775 | 0.77 | CHRM1 (0.42) | — | |
| SCHEMBL2808804 | 0.76 | REN (0.55) | ALDH1A1TSHR | |
| SCHEMBL8286485 | 0.74 | PDE4B (0.36) | BACE1OPRM1OPRL1NAMPTALDH1A1 | |
| SCHEMBL3069018 | 0.74 | TDP1 (0.36) | BACE1CPT2CPT1ACPT1BRXFP1 | |
| SCHEMBL2805180 | 0.74 | REN (0.48) | ALDH1A1TSHR | |
| SCHEMBL2339596 | 0.72 | TSHR (0.56) | TSHR | |
| SCHEMBL13434145 | 0.71 | REN (0.40) | OPRM1OPRL1RXFP1ALDH1A1TSHR | |
| SCHEMBL3074451 | 0.70 | KMT2A (0.40) | OPRM1OPRL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707202-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |