Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910346 | 0.90 | GRM2 (0.45) | GRM2KMOL3MBTL1TSHR | |
| SCHEMBL13210476 | 0.90 | GRM2 (0.44) | GRM2KMOL3MBTL1GAATSHR | |
| SCHEMBL8285824 | 0.87 | GRM2 (0.46) | GRM2KMOL3MBTL1GAATSHR | |
| SCHEMBL8284812 | 0.86 | GRM2 (0.45) | GRM2KMOL3MBTL1TSHR | |
| SCHEMBL13210385 | 0.86 | GRM2 (0.43) | GRM2KMOL3MBTL1GAATSHR | |
| SCHEMBL2905908 | 0.86 | PDE4B (0.43) | GRM2KMOL3MBTL1 | |
| SCHEMBL8284806 | 0.86 | GRM2 (0.39) | GRM2KMOGAATSHRKDM4C | |
| SCHEMBL2908741 | 0.85 | GRM2 (0.44) | GRM2L3MBTL1TSHR | |
| SCHEMBL2903330 | 0.84 | GRM2 (0.42) | GRM2L3MBTL1 | |
| SCHEMBL2908377 | 0.82 | LTC4S (0.42) | GRM2L3MBTL1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061458-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |