Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14451499 | 1.00 | PARP15 (0.50) | PARP15PARP10PARP2ARMMP13 | |
| SCHEMBL8285682 | 0.89 | KAT6A (0.51) | PARP15PARP10PARP2ARMMP13 | |
| SCHEMBL5513674 | 0.88 | PDE4A (0.54) | PARP15PARP10PARP2MMP13NR1H4 | |
| SCHEMBL5513669 | 0.88 | PDE4A (0.54) | PARP15PARP10PARP2MMP13NR1H4 | |
| SCHEMBL5521806 | 0.88 | HDAC3 (0.51) | PARP15PARP10PARP2ARNR1H4 | |
| SCHEMBL5523321 | 0.88 | HDAC3 (0.51) | PARP15PARP10PARP2ARNR1H4 | |
| SCHEMBL5521812 | 0.88 | HDAC3 (0.51) | PARP15PARP10PARP2ARNR1H4 | |
| SCHEMBL5517528 | 0.86 | SMN1; SMN2 (0.44) | ARGABRA5CHRM4 | |
| SCHEMBL5519281 | 0.86 | HPGD (0.49) | PARP15PARP10PARP2 | |
| SCHEMBL5523245 | 0.86 | HPGD (0.49) | PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080317-A2 | THERAPEUTIC AMIDE DERIVATIVES | PFIZER JAPAN, INC. (JP) | 2005-09-01 | — | — | WO | disclosed |