Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14451499 | 0.89 | PARP15 (0.50) | MMP13NR1H4ARPARP15PARP10 | |
| SCHEMBL8285679 | 0.89 | PARP15 (0.50) | MMP13NR1H4ARPARP15PARP10 | |
| SCHEMBL5518008 | 0.84 | KAT6A (0.45) | KAT6ANR1H4PARP15PARP10PARP2 | |
| SCHEMBL5518002 | 0.84 | KAT6A (0.45) | KAT6ANR1H4PARP15PARP10PARP2 | |
| SCHEMBL5518006 | 0.84 | KAT6A (0.45) | KAT6ANR1H4PARP15PARP10PARP2 | |
| SCHEMBL5523321 | 0.84 | HDAC3 (0.51) | MEN1KMT2AHDAC6NR1H4AR | |
| SCHEMBL5521806 | 0.84 | HDAC3 (0.51) | MEN1KMT2AHDAC6NR1H4AR | |
| SCHEMBL5521812 | 0.84 | HDAC3 (0.51) | MEN1KMT2AHDAC6NR1H4AR | |
| SCHEMBL5513674 | 0.82 | PDE4A (0.54) | MMP13NR1H4PARP15PARP10PARP2 | |
| SCHEMBL5513669 | 0.82 | PDE4A (0.54) | MMP13NR1H4PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080317-A2 | THERAPEUTIC AMIDE DERIVATIVES | PFIZER JAPAN, INC. (JP) | 2005-09-01 | — | — | WO | disclosed |