Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cardiogenol C SCHEMBL29766906 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| Cardiogenol C SCHEMBL30628562 | 0.99 | ALDH1A1 (0.68) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL8287302 | 0.85 | AURKA (0.51) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL31059888 | 0.82 | AURKA (0.62) | MAPTMAPK1NPC1RAB9ACDK2 | |
| SCHEMBL8287024 | 0.82 | AURKA (0.62) | MAPTMAPK1NPC1RAB9ACDK2 | |
| SCHEMBL14811109 | 0.81 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL10359051 | 0.80 | ALDH1A1 (0.89) | ALDH1A1MAPTMEN1KMT2AGBA1 | |
| SCHEMBL2177165 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2175149 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL15137019 | 0.77 | MEN1 (0.72) | ALDH1A1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611457-B2 | Triazine derivatives as differentiation catalysts | TECHNISCHE UNIVERSITAET WIEN (AT) | 2017-04-04 | — | — | US | disclosed |
| US-9611457-B2 | Triazine derivatives as differentiation catalysts | TECHNISCHE UNIVERSITAET WIEN (AT) | 2017-04-04 | — | — | US | disclosed |
| US-20140234965-A1 | TRIAZINE DERIVATIVES AS DIFFERENTIATION CATALYSTS | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2014-08-21 | — | — | US | disclosed |
| US-20140234965-A1 | TRIAZINE DERIVATIVES AS DIFFERENTIATION CATALYSTS | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2014-08-21 | — | — | US | disclosed |
| WO-2005068437-A1 | 2, 4 - DIAMINOPYRIMIDINES AND THEIR USE FOR INDUCING CARDIOMYOGENESIS | NOVARTIS AG (CH) | 2005-07-28 | — | — | WO | disclosed |