Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | GPR6 | P46095 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3903764 | 0.96 | IRAK4 (0.49) | IRAK4IRAK1F10GPR6SMN1; SMN2 | |
| SCHEMBL8265127 | 0.92 | F10 (0.51) | IRAK4IRAK1F10SMN1; SMN2TDP1 | |
| Trifluoroacetic Acid SCHEMBL3156028 | 0.90 | F10 (0.47) | IRAK4IRAK1F10SMN1; SMN2TDP1 | |
| SCHEMBL4277026 | 0.88 | IRAK4 (0.50) | IRAK4IRAK1F10NPC1RAB9A | |
| SCHEMBL4277506 | 0.88 | NPC1 (0.58) | IRAK4IRAK1F10SMN1; SMN2NPC1 | |
| SCHEMBL8286232 | 0.88 | IRAK4 (0.50) | IRAK4IRAK1F10NPC1RAB9A | |
| SCHEMBL3905726 | 0.87 | IRAK4 (0.48) | IRAK4IRAK1F10SMN1; SMN2NPC1 | |
| SCHEMBL4269020 | 0.87 | IRAK4 (0.49) | IRAK4IRAK1F10GPR6NPC1 | |
| SCHEMBL4279736 | 0.87 | IRAK4 (0.49) | IRAK4IRAK1F10NPC1RAB9A | |
| SCHEMBL8285066 | 0.87 | F10 (0.48) | IRAK4IRAK1F10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511066-B2 | Antithrombotic aromatic ethers | ELI LILLY AND COMPANY (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511066-B2 | Antithrombotic aromatic ethers | ELI LILLY AND COMPANY (US) | 2009-03-31 | — | — | US | disclosed |
| US-20070027185-A1 | Antithrombotic aromatic ethers | ELILILLY AND COMPANY (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070027185-A1 | Antithrombotic aromatic ethers | ELILILLY AND COMPANY (US) | 2007-02-01 | — | — | US | disclosed |
| WO-2005049604-A2 | ANTITHROMBOTIC AROMATIC ETHERS | ELI LILLY AND COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027185-A1 | Antithrombotic aromatic ethers | F2, F11, TFPI | IRAK4 1883/4885IRAK1 742/4885F10 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.