Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299579 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 | |
| SCHEMBL4299584 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 | |
| SCHEMBL13970640 | 0.88 | PDE4D (0.39) | MAPTSMN1; SMN2PDE4BTUBB4ATUBB | |
| SCHEMBL4310212 | 0.84 | P2RX3 (0.43) | MAPTNR1H2NR1H3SYKAURKB | |
| SCHEMBL4310215 | 0.84 | P2RX3 (0.43) | MAPTNR1H2NR1H3SYKAURKB | |
| SCHEMBL4301095 | 0.83 | MEN1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 | |
| SCHEMBL4301090 | 0.83 | MEN1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 | |
| SCHEMBL4299508 | 0.83 | AKR1C3 (0.39) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 | |
| SCHEMBL4299504 | 0.83 | AKR1C3 (0.39) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 | |
| SCHEMBL4301488 | 0.82 | NPC1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087726-A1 | NOVEL ARYL-CONTAINING 5-ACYLINDOLINONES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-09-22 | — | — | WO | disclosed |