Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 5/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903857 | 0.88 | TBK1 (0.40) | PTGDRPRNPGPR6ADORA2AADORA1 | |
| SCHEMBL8287160 | 0.85 | PTGDR (0.42) | PTGDRPRNPMAP3K7PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL3903120 | 0.82 | PTGDR (0.40) | PTGDRPRNPGPR6FLT3 | |
| SCHEMBL3160242 | 0.79 | METAP1 (0.44) | PTGDRPRNPPDE4BNPC1RAB9A | |
| SCHEMBL3903799 | 0.78 | TXK (0.39) | GPR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3904310 | 0.77 | TOP2A (0.40) | GPR6PDE4BMAPT | |
| SCHEMBL3159855 | 0.76 | KDM1A (0.45) | PTGDRPRNPNPC1RAB9AFLT3 | |
| SCHEMBL8286962 | 0.76 | ATR (0.39) | GPR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3904231 | 0.75 | TOP2A (0.45) | GPR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8285039 | 0.75 | GRM5 (0.43) | GPR6PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049604-A2 | ANTITHROMBOTIC AROMATIC ETHERS | ELI LILLY AND COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |