Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 13/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405641 | 0.89 | GHSR (0.57) | GHSRAGTR1XIAP | |
| SCHEMBL9025480 | 0.89 | GHSR (0.57) | GHSRAGTR1XIAP | |
| SCHEMBL9405602 | 0.89 | GHSR (0.55) | GHSRAGTR1XIAP | |
| SCHEMBL9024460 | 0.89 | GHSR (0.55) | GHSRAGTR1XIAP | |
| SCHEMBL9024337 | 0.86 | GHSR (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL9025207 | 0.85 | GHSR (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL9179425 | 0.85 | GHSR (0.51) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9179437 | 0.85 | GHSR (0.51) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7795408 | 0.84 | GHSR (0.56) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9106313 | 0.84 | GHSR (0.56) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058308-A2 | TREATMENT FOR ALZHEIMER'S DISEASE AND RELATED CONDITIONS | MERCK SHARP & DOHME LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |