Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | MIF | P14174 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iguratimod SCHEMBL29366981 | 0.85 | PTGS1 (1.00) | ADORA3MIFPTGS1PDE4APDE4D | |
| Iguratimod SCHEMBL26326 | 0.85 | PTGS1 (1.00) | ADORA3MIFPTGS1PDE4APDE4D | |
| Iguratimod SCHEMBL5455197 | 0.84 | PTGS1 (0.98) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL7863101 | 0.83 | PTGS1 (0.81) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL8295858 | 0.83 | ADORA3 (0.71) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL31114276 | 0.81 | PTGS1 (0.77) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL30753982 | 0.81 | PTGS1 (0.77) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL14879256 | 0.80 | ADORA3 (0.67) | ADORA3MIFPTGS1PDE4APDE4D | |
| Iguratimod SCHEMBL29230458 | 0.79 | PTGS1 (0.87) | ADORA3MIFPTGS1PDE4APDE4D | |
| SCHEMBL13823409 | 0.78 | ADORA3 (0.72) | ADORA3MIFPTGS1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037193-A2 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR ADMINISTERED UNDER HYPOTHERMIC CONDITIONS FOR THE TREATMENT OF ISCHEMIC MEDIATED CENTRAL NERVOUS SYSTEM DISORDERS OR INJURY | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005007106-A2 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A NON-NMDA GLUTAMATE MODULATOR FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE | PHARMACIA CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |