Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL858117 | 0.76 | PARP1 (0.34) | — | |
| SCHEMBL17511896 | 0.74 | PI4KA (0.43) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL857163 | 0.73 | PARP1 (0.32) | EGFR | |
| SCHEMBL857349 | 0.71 | EGFR (0.32) | EGFR | |
| SCHEMBL855664 | 0.71 | NR4A2 (0.38) | EGFRMAPTALDH1A1RAB9ALIMK1 | |
| SCHEMBL855067 | 0.70 | HTT (0.38) | EGFRMAPTALDH1A1GLAHPGD | |
| SCHEMBL855850 | 0.70 | KDM4E (0.33) | MEN1KMT2AMAP4K4 | |
| SCHEMBL856169 | 0.70 | MAP4K4 (0.39) | KMT2AMAP4K4 | |
| SCHEMBL275756 | 0.70 | MAPT (0.41) | MAPTALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL8358 | 0.68 | ALDH1A1 (0.38) | EGFRMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4391 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019736-A | Molecular gel compound designed based on cereblon protein and application thereof | 标新生物医药科技(上海)有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2024051766-A1 | MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-03-14 | — | — | WO | claimed |
| EP-4329755-A1 | EXPANDED DOSAGE REGIMENS FOR INTEGRIN INHIBITORS | Pliant Therapeutics, Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| WO-2024040497-A1 | ANTIVIRAL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-02-29 | — | — | WO | claimed |
| EP-4328230-A2 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | claimed |
| CN-117615760-A | Extended dosage regimen for integrin inhibitors | 普利安特治疗公司 | 2024-02-27 | — | — | CN | claimed |
| US-20240059726-A1 | GLYCOSYLATED HISTONE DEACETYLASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GEORGIA TECH RESEARCH CORPORATION | 2024-02-22 | — | — | US | claimed |
| CN-113166119-B | Substituted aryl compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| EP-3761980-B1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS INC (US) | 2023-11-29 | — | — | EP | claimed |
| EP-4247389-A1 | GLYCOSYLATED HISTONE DEACETYLASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | Georgia Tech Research Corporation (US) | 2023-09-27 | — | — | EP | claimed |
| EP-0313296-A2 | Substituted chromans and related compounds in the treatment of asthma | PFIZER INC. (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0313295-A2 | Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0184841-A2 | 1,4-Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1986-06-18 | — | — | EP | claimed |
| EP-0118528-A4 | 5-(BICYCLIC NITROGEN-HETEROARYL)PYRID-2-ONES AND THEIR USE FOR INCREASING CARDIAC CONTRACTILITY. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-09 | — | — | EP | claimed |
| EP-0118528-A1 | 5-(BICYCLIC NITROGEN-HETEROARYL)PYRID-2-ONES AND THEIR USE FOR INCREASING CARDIAC CONTRACTILITY | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1984-09-19 | — | — | EP | claimed |
| WO-1984000756-A1 | 5 (BICYCLIC NITROGEN-HETEROARYL)PYRID-2-ONES AND THEIR USE FOR INCREASING CARDIAC CONTRACTILLITY | RORER INT OVERSEAS (US) | 1984-03-01 | — | — | WO | claimed |
| US-4379154-A | Thiocarboxamide derivatives and their use as pharmaceuticals | RHONE-POULENC SANTE (FR) | 1983-04-05 | — | — | US | claimed |
| US-4294581-A | ANTHRAQUINONE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | claimed |
| EP-0000346-B1 | QUINOXALINE COMPOUNDS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS BRIGHTENERS FOR ORGANIC MATERIALS, AND THE MATERIALS BRIGHTENED THEREWITH | BAYER AG (DE) | 1980-01-09 | — | — | EP | claimed |
| EP-0000346-A1 | Quinoxaline compounds, process for their manufacture and their use as brighteners for organic materials, and the materials brightened therewith | BAYER AG (DE) | 1979-01-24 | — | — | EP | claimed |