Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13347220 | 0.89 | EPHX2 (0.40) | — | |
| SCHEMBL13347221 | 0.88 | MEN1 (0.47) | GAAHTT | |
| SCHEMBL13347219 | 0.88 | MEN1 (0.47) | GAAHTT | |
| SCHEMBL8288233 | 0.87 | DPP4 (0.46) | ALDH1A1TSHRHPGDNPC1CYP2C19 | |
| SCHEMBL8286521 | 0.82 | MEN1 (0.46) | ALDH1A1GAAHTT | |
| SCHEMBL8214183 | 0.82 | EPHX2 (0.41) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8216780 | 0.80 | MAPT (0.52) | ALDH1A1KDM4EGAACYP3A4CYP2D6 | |
| SCHEMBL8214083 | 0.80 | LMNA (0.47) | ALDH1A1TSHRHPGDNPC1CYP2C19 | |
| SCHEMBL8218681 | 0.78 | AKR1C3 (0.51) | ALDH1A1GAA | |
| SCHEMBL8218676 | 0.77 | AKR1C3 (0.55) | ALDH1A1TSHRHPGDPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047297-A1 | HETEROCYCLIC BORONIC ACID COMPOUNDS | PHENOMIX CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |