Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325757 | 0.85 | KDM4E (0.61) | DPP4ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL29375817 | 0.85 | KDM4E (0.61) | DPP4ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL5480089 | 0.84 | KDM4E (0.59) | DPP4ALDH1A1KDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL6175383 | 0.82 | KDM4E (0.58) | DPP4ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL15780138 | 0.82 | DPP4 (0.53) | DPP4ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL3816637 | 0.79 | DPP4 (1.00) | DPP4 | |
| SCHEMBL13347175 | 0.79 | DPP4 (0.76) | DPP4FAPDPP7 | |
| SCHEMBL3816645 | 0.79 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2386976 | 0.78 | ALDH1A1 (0.86) | ALDH1A1TSHRHPGDSMN1; SMN2LMNA | |
| SCHEMBL1826063 | 0.78 | ALDH1A1 (0.86) | ALDH1A1TSHRHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047297-A1 | HETEROCYCLIC BORONIC ACID COMPOUNDS | PHENOMIX CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |