Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860252 | 0.84 | KCNH2 (0.53) | MAOBKCNH2RAB9AMEN1NPC1 | |
| SCHEMBL8285904 | 0.81 | CYP3A4 (0.53) | MAOBKCNH2 | |
| SCHEMBL29468863 | 0.80 | FFAR1 (0.44) | KCNH2MAPTMRGPRX4ALOX5AP | |
| SCHEMBL24726479 | 0.79 | KCNH2 (0.47) | KCNH2MEN1LMNAHPGDKMT2A | |
| SCHEMBL16710556 | 0.79 | KCNH2 (0.47) | MAOBKCNH2MRGPRX4 | |
| SCHEMBL29468767 | 0.78 | MAOB (0.60) | MAOBKCNH2RAB9AMEN1KMT2A | |
| SCHEMBL2649525 | 0.78 | MAOB (0.60) | MAOBKCNH2RAB9AMEN1KMT2A | |
| SCHEMBL8288265 | 0.78 | KCNH2 (0.49) | MAOBKCNH2MAPTSMN1; SMN2 | |
| SCHEMBL13232411 | 0.77 | KCNH2 (0.56) | KCNH2RAB9AMEN1NPC1LMNA | |
| SCHEMBL10690028 | 0.76 | CYSLTR1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044265-A1 | ALKYNES III | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | WO | disclosed |