Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.55 |
| ▸ | MAX | P61244 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905044 | 0.87 | MEN1 (0.68) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3905040 | 0.87 | MEN1 (0.68) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8189877 | 0.85 | KMT2A (0.67) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8189873 | 0.85 | KMT2A (0.67) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8189870 | 0.85 | KMT2A (0.67) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3895449 | 0.85 | MEN1 (0.65) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3895447 | 0.85 | MEN1 (0.65) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3126558 | 0.81 | POLB (0.80) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3126561 | 0.81 | POLB (0.80) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3126564 | 0.81 | POLB (0.80) | MEN1KMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |