Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | RECQL | P46063 | 5/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | MAX | P61244 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189877 | 1.00 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL8189873 | 1.00 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3905040 | 0.87 | MEN1 (0.68) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3905044 | 0.87 | MEN1 (0.68) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3133705 | 0.86 | MAPT (0.72) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3133695 | 0.86 | MAPT (0.72) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3133698 | 0.86 | MAPT (0.72) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL8288288 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3895447 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL3895449 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032598-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISEASES UTILIZING INHIBITORS OF TUMOR NECROSIS FACTOR ACTIVITY | STRUCTURAL BIOINFORMATICS INC. (US) | 2000-06-08 | — | — | WO | disclosed |