Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23394146 | 1.00 | HPGD (0.56) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12902 | 0.95 | ALDH1A1 (0.56) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12908 | 0.95 | ALDH1A1 (0.56) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL771303 | 0.95 | ALDH1A1 (0.56) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL21336690 | 0.90 | HPGD (0.64) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8056889 | 0.88 | RECQL (0.54) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL264879 | 0.88 | RECQL (0.54) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8276848 | 0.88 | RECQL (0.54) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL19012969 | 0.87 | HPGD (0.56) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL22765858 | 0.84 | HPGD (0.66) | HPGDALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058311-A1 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2005-06-30 | — | — | WO | disclosed |