Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.58 |
| ▸ | CCKBR | P32239 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10540800 | 0.92 | ADORA3 (0.60) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL8286960 | 0.87 | MEN1 (0.73) | ADORA3NR1I2NR3C1TBXA2RPDE4D | |
| SCHEMBL10712075 | 0.86 | ADORA3 (0.57) | ADORA3NR1I2NR3C1TBXA2RCCKBR | |
| SCHEMBL11004140 | 0.85 | CACNA1C (0.72) | ADORA3NR1I2NR3C1TBXA2RCCKBR | |
| SCHEMBL8288455 | 0.85 | ADORA3 (0.74) | ADORA3NR1I2NR3C1TBXA2RPDE4D | |
| SCHEMBL9733144 | 0.84 | CACNA1C (0.62) | ADORA3NR1I2NR3C1TBXA2RCCKBR | |
| SCHEMBL7160394 | 0.83 | CACNA1C (0.77) | ADORA3NR1I2NR3C1TBXA2RCCKBR | |
| SCHEMBL19017149 | 0.83 | ADORA3 (0.60) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7159699 | 0.82 | ADORA3 (0.81) | ADORA3NR1I2NR3C1TBXA2RCCKBR | |
| SCHEMBL30357961 | 0.82 | ADORA3 (0.81) | ADORA3NR1I2NR3C1TBXA2RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042486-A1 | 1,4-DIHYDROPYRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | MYOGEN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |