Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.73 |
| ▸ | FLT3 | P36888 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288811 | 0.99 | ANO1 (0.71) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL8289690 | 0.85 | ANO1 (1.00) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL3924390 | 0.83 | ANO1 (0.97) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL8289496 | 0.83 | MAPT (0.68) | ANO1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8289832 | 0.81 | ANO1 (0.92) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL8289718 | 0.81 | FLT3 (0.97) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL4132192 | 0.80 | ANO1 (0.76) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL3914847 | 0.79 | FLT3 (1.00) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL5453572 | 0.78 | ANO1 (0.73) | ANO1FLT3KMT2AMEN1CYP1A2 | |
| SCHEMBL8288839 | 0.78 | ANO1 (0.72) | ANO1FLT3KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |