Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | FLT3 | P36888 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924390 | 0.97 | ANO1 (0.97) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL8289690 | 0.96 | ANO1 (1.00) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL8289415 | 0.84 | KDM4E (1.00) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL8290656 | 0.83 | KDM4E (0.68) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL5453572 | 0.83 | ANO1 (0.73) | ANO1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8288772 | 0.82 | KDM4E (0.74) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL8288811 | 0.82 | ANO1 (0.71) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL4132192 | 0.82 | ANO1 (0.76) | ANO1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5467520 | 0.81 | ANO1 (0.67) | ANO1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL8288694 | 0.81 | ANO1 (0.73) | ANO1ALDH1A1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |