Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.83 |
| ▸ | MAPT | P10636 | 8/20 | 0.83 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | FNTA | P49354 | 1/20 | 0.64 |
| ▸ | FNTB | P49356 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290398 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL31209766 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL8289662 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL31209890 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL12443339 | 0.76 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL8289695 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL27075492 | 0.71 | HSD17B10 (0.67) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL7003055 | 0.69 | AIP (0.74) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL23827451 | 0.68 | ALDH1A1 (0.81) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 | |
| SCHEMBL7003174 | 0.67 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTAPOBEC3GMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |