Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 16/20 | 0.66 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141384 | 0.99 | GRM1 (0.65) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL4152901 | 0.85 | GRM1 (0.81) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL3280341 | 0.84 | ALDH1A1 (0.73) | GRM1ALDH1A1MAPTGAAHPGD | |
| SCHEMBL6861991 | 0.81 | GRM1 (0.67) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL29383334 | 0.80 | HPGD (0.76) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL1007269 | 0.79 | GRM1 (1.00) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL1007297 | 0.79 | GRM1 (0.87) | GRM1GRIA2ALDH1A1GAAHPGD | |
| SCHEMBL3452590 | 0.79 | GRM1 (0.62) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL1007789 | 0.78 | GRM1 (0.68) | GRM1GRIA2ALDH1A1MAPTGAA | |
| SCHEMBL1008341 | 0.78 | GRM1 (0.71) | GRM1GRIA2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |