Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6104841 | 0.91 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6104837 | 0.91 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6104518 | 0.90 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL5767228 | 0.90 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6104524 | 0.90 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6103480 | 0.90 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6107414 | 0.90 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL5648617 | 0.89 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6104297 | 0.89 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6106574 | 0.89 | PTGS2 (0.67) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037193-A2 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR ADMINISTERED UNDER HYPOTHERMIC CONDITIONS FOR THE TREATMENT OF ISCHEMIC MEDIATED CENTRAL NERVOUS SYSTEM DISORDERS OR INJURY | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |