Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.61 |
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 8/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124005 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL28100314 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1MASP2 | |
| SCHEMBL7870187 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL197989 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL197990 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL25396765 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL8512122 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL20011747 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL199332 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 | |
| SCHEMBL5201978 | 0.86 | HDAC2 (0.65) | HDAC2DPP4F2RPS6KB1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385870-B1 | PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1467989-B1 | PROLINE COMPOUNDS AS NS3-SERINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF HEPATITIS C VIRUS INFECTION | SCHERING CORP (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-2003062265-A2 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |