Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182529 | 0.83 | CYP19A1 (0.45) | CYP19A1DGAT1 | |
| SCHEMBL84526 | 0.77 | CYP19A1 (0.48) | CYP19A1DGAT1 | |
| SCHEMBL20306236 | 0.72 | CYP19A1 (0.45) | CYP19A1DGAT1 | |
| SCHEMBL26787597 | 0.72 | CYP19A1 (0.45) | CYP19A1 | |
| SCHEMBL8863475 | 0.72 | CYP19A1 (0.45) | CYP19A1DGAT1 | |
| SCHEMBL25072259 | 0.72 | CYP19A1 (0.50) | CYP19A1 | |
| SCHEMBL12523344 | 0.69 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL27904846 | 0.69 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL14389114 | 0.69 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL22785831 | 0.67 | SHBG (0.45) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796697-B2 | Tricyclic inhibitors of HIF-2-alpha and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| WO-2005040110-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |