Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059451 | 0.88 | DPP4 (0.56) | DPP4CYP3A4 | |
| SCHEMBL13139857 | 0.88 | DPP4 (0.56) | DPP4CYP3A4 | |
| SCHEMBL5583922 | 0.80 | HPGD (0.48) | ALDH1A1KDM4ETNKSPARP1TNKS2 | |
| SCHEMBL8290094 | 0.78 | DPP4 (0.44) | ALDH1A1KDM4ETNKSPARP1TNKS2 | |
| SCHEMBL8291759 | 0.71 | DPP4 (0.46) | ALDH1A1KDM4ETNKSPARP1TNKS2 | |
| SCHEMBL3063723 | 0.68 | DPP4 (0.59) | DPP4CYP3A4 | |
| SCHEMBL13139853 | 0.68 | DPP4 (0.59) | DPP4CYP3A4 | |
| SCHEMBL213726 | 0.67 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2NPSR1ADORA2A | |
| SCHEMBL2735175 | 0.67 | PDE9A (0.48) | ALDH1A1KDM4ETNKSPARP1TNKS2 | |
| SCHEMBL3073729 | 0.67 | DPP4 (0.54) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699777-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2012-12-12 | — | — | EP | disclosed |
| WO-2005026148-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-03-24 | — | — | WO | disclosed |