Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288214 | 0.93 | DPP4 (0.68) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8290050 | 0.93 | DPP4 (0.69) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8290047 | 0.91 | DPP4 (0.64) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8290104 | 0.90 | DPP4 (0.60) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL6444430 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8289042 | 0.86 | DPP4 (0.63) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL4664756 | 0.85 | DPP4 (0.68) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8289074 | 0.85 | DPP4 (0.68) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8289039 | 0.84 | DPP4 (0.68) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL14535255 | 0.83 | DPP4 (0.77) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |