Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685078 | 1.00 | CTSV (0.35) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL12608361 | 1.00 | CTSV (0.35) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL16349671 | 0.95 | CTSV (0.33) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL16349686 | 0.95 | CTSV (0.33) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13685337 | 0.90 | CTSV (0.34) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13685005 | 0.90 | CTSV (0.34) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13685690 | 0.89 | CTSV (0.35) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13685318 | 0.87 | F2 (0.34) | — | |
| SCHEMBL8290298 | 0.87 | F2 (0.34) | — | |
| SCHEMBL7858719 | 0.87 | F2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |