Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | CASP3 | P42574 | 1/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.71 |
| ▸ | TLR2 | O60603 | 2/20 | 0.68 |
| ▸ | FLT3 | P36888 | 6/20 | 0.67 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.64 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.60 |
| ▸ | CFTR | P13569 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450860 | 0.97 | MEN1 (0.78) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5448370 | 0.90 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL18015730 | 0.89 | KCNH2 (0.71) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5455976 | 0.87 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4234573 | 0.86 | FLT3 (0.72) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8288770 | 0.86 | FLT3 (0.68) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5455065 | 0.85 | MEN1 (0.79) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5462791 | 0.85 | FLT3 (0.72) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5467902 | 0.85 | FLT3 (0.72) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5446174 | 0.84 | FLT3 (0.71) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |