Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120273 | 0.84 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4PTGER4LMNA | |
| SCHEMBL4631275 | 0.84 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4LMNA | |
| SCHEMBL8125695 | 0.77 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4PTGER4 | |
| SCHEMBL8563823 | 0.76 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8562592 | 0.76 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9318198 | 0.75 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8558548 | 0.74 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5891959 | 0.74 | POLB (0.38) | SLC6A3PTGER4 | |
| SCHEMBL4630703 | 0.74 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13686149 | 0.74 | SLC6A3 (0.46) | SLC6A3SLC6A2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512901-B1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-06-23 | — | — | EP | disclosed |
| EP-0512901-A1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-11 | — | — | EP | disclosed |