Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755454 | 0.80 | PDE4A (0.69) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6865053 | 0.79 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL5567417 | 0.79 | PDE4A (0.67) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6865665 | 0.77 | PDE4A (0.55) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7900923 | 0.76 | PDE4A (0.66) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7911123 | 0.75 | PDE4A (0.60) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6582977 | 0.75 | PDE4A (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6583750 | 0.75 | PDE4A (0.58) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL13652961 | 0.74 | PDE4A (0.67) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL15790501 | 0.74 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626957-B1 | STYRIL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LTD (GB) | 1999-03-03 | — | — | EP | disclosed |