Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | XPA | P23025 | 8/20 | 0.59 |
| ▸ | GSK3A | P49840 | 3/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291312 | 0.89 | KMT2A (0.72) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL8290432 | 0.80 | ESR2 (0.72) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL8290360 | 0.79 | ESR2 (0.81) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL19419927 | 0.79 | ESR2 (0.69) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL13708915 | 0.78 | ESR2 (0.62) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL19425313 | 0.78 | ESR2 (0.62) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL8291279 | 0.78 | ESR2 (0.66) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL14584108 | 0.77 | ESR2 (0.62) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL12027509 | 0.76 | GSK3A (0.84) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL8291189 | 0.75 | POLB (0.44) | ALDH1A1KMT2APOLBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005034940-A2 | DUAL ALANYL AMINOPEPTIDASE AND DIPEPTIDYL PEPTIDASE IV INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND FOR TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-21 | — | — | WO | disclosed |