⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408750 | 0.79 | KDM4E (0.43) | — | |
| SCHEMBL18774433 | 0.74 | — | — | |
| SCHEMBL15144321 | 0.74 | GAA (0.42) | — | |
| SCHEMBL16193202 | 0.74 | KDM4E (0.40) | — | |
| SCHEMBL1105653 | 0.74 | — | — | |
| SCHEMBL314795 | 0.74 | — | — | |
| SCHEMBL1562317 | 0.72 | — | — | |
| SCHEMBL18045691 | 0.72 | GAA (0.45) | — | |
| Potassium SCHEMBL30426704 | 0.72 | — | — | |
| SCHEMBL7263711 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020150919-A1 | Methods for identifying genes associated with diseases or specific phenotypes | YALE UNIVERSITY | 2002-10-17 | — | — | US | claimed |
| WO-2002034949-A2 | METHODS FOR IDENTIFYING GENES ASSOCIATED WITH DISEASES OR SPECIFIC PHENOTYPES | MOLECULAR STAGING INC. (US) | 2002-05-02 | — | — | WO | claimed |
| EP-0516074-B1 | Aqueous dispersions of carbonylgroup-containing copolymers, further containing aminoxy-curing agents | WACKER CHEMIE GMBH (DE) | 1995-09-27 | — | — | EP | claimed |
| US-5278225-A | Comprising (meth)acrylates of alcohol monomer | WACKER-CHEMIE GMBH (DE) | 1994-01-11 | — | — | US | claimed |
| WO-1992007951-A1 | QUANTITATION OF ALDEHYDE-CONTAINING LESIONS IN NUCLEIC ACIDS | KOW YOKE WAH (US) | 1992-05-14 | — | — | WO | claimed |
| US-9957549-B2 | Compositions and methods for negative selection of non-desired nucleic acid sequences | NUGEN TECHNOLOGIES, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| EP-2861787-B1 | COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES | NUGEN TECH INC (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20160362680-A1 | COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES | NUGEN TECHNOLOGIES, INC. | 2016-12-15 | — | — | US | disclosed |
| US-20150299767-A1 | COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES | NUGEN TECHNOLOGIES, INC. | 2015-10-22 | — | — | US | disclosed |
| EP-2604702-B1 | Methods for direct detection of DNA damage | UNIV CHICAGO (US) | 2015-07-01 | — | — | EP | disclosed |
| EP-2861787-A2 | COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES | Nugen Technologies, Inc. (US) | 2015-04-22 | — | — | EP | disclosed |
| US-20140220696-A1 | METHODS AND COMPOSITIONS FOR DIRECT DETECTION OF DNA DAMAGE | UNIVERSITY OF CHICAGO (US) | 2014-08-07 | — | — | US | disclosed |
| EP-1060266-A1 | METHOD FOR IDENTIFYING MISMATCH REPAIR GLYCOSYLASE REACTIVE SITES, COMPOUND AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-2000039345-A1 | MUTATION SCANNING ARRAY, AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2000-07-06 | — | — | WO | disclosed |
| WO-1999042622-A1 | METHOD FOR IDENTIFYING MISMATCH REPAIR GLYCOSYLASE REACTIVE SITES, COMPOUND AND USES THEREOF_____________________________________ | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1999-08-26 | — | — | WO | disclosed |
| US-5278225-A | Comprising (meth)acrylates of alcohol monomer | WACKER-CHEMIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |
| WO-1992007951-A1 | QUANTITATION OF ALDEHYDE-CONTAINING LESIONS IN NUCLEIC ACIDS | KOW YOKE WAH (US) | 1992-05-14 | — | — | WO | disclosed |
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0438752-A1 | Monobactam hydrazides containing catechol sulfonic acid groups | E.R. SQUIBB & SONS, INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5030724-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-07-09 | — | — | US | disclosed |