Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281042 | 0.80 | MEN1 (0.51) | OPRM1OPRD1OPRK1CALM1CAMKK2 | |
| SCHEMBL14376856 | 0.79 | MAOB (0.56) | BCHETAAR1MAOB | |
| SCHEMBL14608016 | 0.78 | TAAR1 (0.53) | TAAR1MAOBSLC6A4SLC6A3 | |
| SCHEMBL8281044 | 0.76 | MEN1 (0.51) | CALM1CAMKK2 | |
| SCHEMBL14012776 | 0.76 | ACKR3 (0.47) | BCHECALM1CAMKK2 | |
| SCHEMBL24965971 | 0.75 | TAAR1 (0.57) | TAAR1MAOBSLC6A4SLC6A3 | |
| SCHEMBL12128568 | 0.75 | TAAR1 (0.58) | BCHETAAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9504529 | 0.74 | MEN1 (0.48) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL27621739 | 0.73 | OPRK1 (0.55) | BCHETAAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL2260874 | 0.73 | OPRK1 (0.59) | TAAR1OPRM1OPRD1OPRK1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005020975-A2 | TREATMENT OF LEARNING DISABILITIES AND MOTOR SKILLS DISORDER WITH NOREPINEPHRINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |