Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301132 | 0.93 | PLA2G2A (0.78) | PLA2G2A | |
| SCHEMBL8293051 | 0.92 | PLA2G2A (0.87) | PLA2G2A | |
| SCHEMBL8300434 | 0.91 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL7953268 | 0.90 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL27398701 | 0.87 | PLA2G2A (0.70) | PLA2G2A | |
| SCHEMBL2006287 | 0.86 | PLA2G2A (0.66) | PLA2G2A | |
| SCHEMBL8291463 | 0.84 | PLA2G2A (0.77) | PLA2G2A | |
| SCHEMBL8292857 | 0.83 | PLA2G2A (0.80) | PLA2G2A | |
| SCHEMBL8296288 | 0.83 | PLA2G2A (0.64) | PLA2G2A | |
| SCHEMBL8292911 | 0.82 | PLA2G2A (0.78) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067986-C | 1H-indole-3-acetic acid hydrazide spla2 inhibitors | LILLY CO ELI (US) | 2001-07-04 | — | — | CN | disclosed |
| EP-0620214-B1 | 1H-indole-3-acetic acid hydrazide sPLA2 inhibitors | LILLY CO ELI (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5578634-A | SEPTIC SHOCK TREATMENT | ELI LILLY AND COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| CN-1098714-A | The 1H-indole-3-acetic acid hydrazide spla 2 inhibitors | LILLY CO ELI (US) | 1995-02-15 | — | — | CN | disclosed |
| EP-0620214-A1 | 1H-indole-3-acetic acid hydrazide sPLA2 inhibitors | ELI LILLY AND COMPANY (US) | 1994-10-19 | — | — | EP | disclosed |