Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338496 | 0.77 | TAAR1 (0.61) | TAAR1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL7701701 | 0.77 | TAAR1 (0.52) | TAAR1GAASMN1; SMN2HTTDAO | |
| SCHEMBL18596074 | 0.76 | TAAR1 (0.43) | TAAR1GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5925042 | 0.72 | MEN1 (0.38) | TAAR1CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5925035 | 0.72 | DAO (0.38) | TAAR1CNR1GAASMN1; SMN2MEN1 | |
| SCHEMBL6085227 | 0.70 | TAAR1 (0.71) | TAAR1GAASMN1; SMN2DAONPSR1 | |
| SCHEMBL13298068 | 0.70 | TAAR1 (0.61) | TAAR1CNR1GAASMN1; SMN2MEN1 | |
| SCHEMBL6206211 | 0.69 | TAAR1 (0.45) | TAAR1GAASMN1; SMN2KMT2ADAO | |
| SCHEMBL172659 | 0.69 | TAAR1 (0.45) | TAAR1GAASMN1; SMN2HTTDAO | |
| SCHEMBL170879 | 0.69 | TAAR1 (0.45) | TAAR1GAASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449447-B2 | Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |