Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6085227 | 0.85 | TAAR1 (0.71) | TAAR1DAOGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL22050353 | 0.84 | KDM4E (0.52) | TAAR1DAOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL249134 | 0.83 | TAAR1 (0.45) | TAAR1DAOKDM4EGAAALDH1A1 | |
| SCHEMBL170879 | 0.83 | TAAR1 (0.45) | TAAR1DAOKDM4EGAAALDH1A1 | |
| SCHEMBL1461202 | 0.83 | TAAR1 (0.45) | TAAR1DAOKDM4EGAAALDH1A1 | |
| SCHEMBL6206211 | 0.83 | TAAR1 (0.45) | TAAR1DAOKDM4EGAAALDH1A1 | |
| SCHEMBL17552668 | 0.83 | TAAR1 (0.45) | TAAR1DAOKDM4EGAAALDH1A1 | |
| SCHEMBL172659 | 0.83 | TAAR1 (0.45) | TAAR1DAOKDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2206528 | 0.83 | TAAR1 (0.68) | TAAR1DAOGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5734084 | 0.81 | TAAR1 (0.54) | TAAR1DAOGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376293-A1 | NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-29 | — | — | US | disclosed |
| US-9382281-B2 | Nickel pre-catalysts and related compositions and methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150141684-A1 | NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-05-21 | — | — | US | disclosed |
| WO-2015070026-A1 | NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-05-14 | — | — | WO | disclosed |
| US-6342504-B1 | PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141684-A1 | NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS | SOD1, NIT2, MPO | TAAR1 4211/4885DAO 2790/4885KDM4E 4170/4885 |
| US-20160376293-A1 | NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS | SOD1, NIT2, MPO | TAAR1 4211/4885DAO 2790/4885KDM4E 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.