Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 14/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296704 | 0.87 | DPP4 (0.42) | EPHX1ALDH1A1ATM | |
| SCHEMBL8296564 | 0.87 | DPP4 (0.42) | EPHX1ALDH1A1ATM | |
| SCHEMBL8294301 | 0.87 | DPP4 (0.42) | EPHX1ALDH1A1ATM | |
| SCHEMBL8296861 | 0.86 | EPHX1 (0.40) | EPHX1EPHX2KDM4EALDH1A1KMT2A | |
| SCHEMBL8296593 | 0.86 | ALDH1A1 (0.51) | EPHX2ALDH1A1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL8295471 | 0.86 | DPP4 (0.40) | KDM4EALDH1A1ATMKMT2A | |
| Hydrochloric Acid SCHEMBL6243138 | 0.85 | DPP4 (0.41) | EPHX1ALDH1A1ATM | |
| SCHEMBL8294342 | 0.85 | DPP4 (0.40) | EPHX1ALDH1A1ATM | |
| SCHEMBL8294193 | 0.83 | DPP4 (0.42) | EPHX1ALDH1A1 | |
| SCHEMBL8295936 | 0.83 | DPP4 (0.37) | EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |